NON-GENETIC ADAPTIVE RESISTANCE TO KRASG12C INHIBITION: EMT IS NOT THE ONLY CULPRIT


Candidates for Repurposing as Anti-Virulence Agents Based on the Structural Profile Analysis of Microbial Collagenase Inhibitors

The pharmacological inhibition of the bacterial collagenases (BC) enzymes is considered a promising strategy to block the virulence of the bacteria without targeting the selection mechanism leading to drug resistance.The chemical structures of the Clostridium perfringens collagenase A (ColA) inhibitors were analyzed using Bemis-Murcko skeletons, Mu

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APLIKASI TEKNOLOGI HURDLE MENGGUNAKAN IRADIASI GAMMA DAN PENYIMPANAN BEKU UNTUK MEREDUKSI BAKTERI PATOGEN PADA BAHAN PANGAN : KAJIAN PUSTAKA

Iradiasi gamma merupakan teknologi pengawetan pangan yang berpotensi untuk digunakan karena tidak menimbulkan perubahan sensoris seperti halnya pada pengawetan pangan konvensional (penggunaan panas).Teknologi ini mampu mereduksi bakteri patogen pada bahan pangan, seperti Escherichia coli, Staphylococcus aureus, Salmonella sp., Vibrio sp., dan Clost

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INTERFERENCES OF THE ENVIRONMENTAL LAW WITH THE URBAN LAW

Addressing the large, complex issue of influences that urbanization can have on the environment, requires first of all, some general considerations on the interferences between the urban law VITAMIN C 1000MG TR and the environmental law.The urban law investigates and regulates the affecting and planning of the urban space.Therefore, this type of re

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